While a recent study shows that poor Atezo/Bev response is associated with high glypican-3 (GPC3) or alpha-fetoprotein (AFP) expression, no correlation was seen between the expression of PD-L1 and Atezo/Bev response – contrary to the data in non-small cell lung cancer or melanoma (112). Here, GPC3 is linked to non-small cell lung carcinoma.