In the post-thrombolysis END group, the NIHSS score after rt-PA for 24 h (p < 0.001), diabetes mellitus (p = 0.003), WBC (p = 0.014), neutrophils (p = 0.003), FBG (p < 0.001), TC (p = 0.001), TG (p < 0.001), AIP (p < 0.001),and NHHR (p < 0.001) were significantly greater than those in the post-thrombolysis non-END group, whereas HDL-C (p < 0.001) was significantly lower than those in the post-thrombolysis non-END group. The gene discussed is AIP; the disease is diabetes mellitus.