C1orf141 and vitiligo: FLJ21901 was the old name of the open reading frame 141 of human chromosome 1 (C1orf141), although the function of the protein it encodes is not fully clear, some studies have found through genome-wide association studies (GWAS) that this gene locus (such as SNPS like rs1126809) is associated with the susceptibility to vitiligo, especially showing a significant association in the East Asian population [14].