As controls, we used iPSC lines that were characterized in previous studies (Figure 1A; Table S1, Supporting Information).[11] Sanger sequencing confirmed the existence of the TMEM43 missense mutation in ARVC but absence in control at the iPSC level (Figure S2G, Supporting Information). The gene discussed is TMEM43; the disease is arrhythmogenic right ventricular cardiomyopathy.