Of the TMEM43‐associated proteins identified in control, ARVC, and GC iPSC‐CMs, 4 were desmosome proteins (plakophilin 2 (PKP2), junction plakoglobin (JUP)) or lamin proteins (lamin A/C, lamin B1) that were previously reported.[24, 25, 26] LINC complex, consisting of nesprins, SUNs, emerin, TMEM43, and lamins, provides structural support to the nucleus and physically couples the nucleoskeleton with the cytoskeleton. The gene discussed is EMD; the disease is arrhythmogenic right ventricular cardiomyopathy.