Of the TMEM43‐associated proteins identified in control, ARVC, and GC iPSC‐CMs, 4 were desmosome proteins (plakophilin 2 (PKP2), junction plakoglobin (JUP)) or lamin proteins (lamin A/C, lamin B1) that were previously reported.[24, 25, 26] LINC complex, consisting of nesprins, SUNs, emerin, TMEM43, and lamins, provides structural support to the nucleus and physically couples the nucleoskeleton with the cytoskeleton. Here, PKP2 is linked to arrhythmogenic right ventricular cardiomyopathy.