NCOA4 and Hepatic fibrosis: Furthermore, exposure to Fe‐rich environmental agents such as diesel particulates and welding fumes has been shown to exacerbate pulmonary and hepatic fibrosis via oxidative stress and ferroptosis pathways.[55, 56, 57] These findings reinforced the possibility that the NCOA4/KLF5 pathway may represent a generalizable mechanism of iron‐driven fibrotic disease induced by environmental pollutants.