In addition, MVI-suggestive findings including irregular tumor margin and arterial rim enhancement, when combined with lower tumor-to-liver signal intensity ratio on HBP images and lower tumor-to-liver apparent diffusion coefficient ratio, are useful for predicting cytokeratin 19 (CK19)-positive HCC, which demonstrates significantly worse recurrence-free survival after curative resection [55]. This evidence concerns the gene KRT19 and hepatocellular carcinoma.