SLC1A2 and amyotrophic lateral sclerosis: Due to the limited effects of CEF treatment and difficulty of exclude the influence of other mechanisms of action of CEF as an antibiotic, we employed LDN‐212320 (also known as OSU‐212320), a small‐molecule agonist that has been reported to extend the lifespan of mice in a model of amyotrophic lateral sclerosis (ALS), to exert a neuroprotective function by increasing translation of GLT‐1.[52] We injected serpinf1−/− mice with 20 mg/kg LDN‐212320 or vehicle for 10 consecutive days and assessed cognitive memory behavior (Figure8A).