KCNT1 and epilepsy: Based on the in vitro analysis and their inhibition of KCNT1 channels, the 4 drugs antrafenine, atorvastatin, nelfinavir mesylate, and regorafenib, were selected to be analyzed in vivo for their effects on the seizure phenotype in 3 humanized Drosophila models of KCNT1 epilepsy.