Studies using the ALL IC reported higher VEGF‐A levels (SMD = 2.164; 95% CI: 0.911–3.417; p = 0.001) compared to those using the FAB classification (SMD = 0.023; 95% CI: −0.514 to 0.559; p = 0.934) or the NCI criteria (SMD = 0.413; 95% CI: 0.056–0.882; p = 0.084). Here, VEGFA is linked to acute lymphoblastic leukemia.