INS and obesity due to melanocortin 4 receptor deficiency: While the connection between obesity and dementia is well‐established [13], our group was the first in showing that the HFD‐induced MONW phenotype (characterized by increased adiposity and altered insulin sensitivity without overt obesity) can also lead to cognitive impairment both in adult and young rats [5, 6].These findings align with previous studies that highlight the vulnerability of the developing brain to early dietary insults, which can result in long‐term cognitive consequences [2].