The relative contribution of TH2 cells and ILC2s to IL‐13 production during HD Tm infection remains to be determined, and although TH2 cells remain the definitive effector cell in expulsion of HD Tm infection, at least in C57BL/6 mice, a role for ILC2s in enabling T cell effector responses continues to be developed. The gene discussed is IL13; the disease is Huntington disease.