It may be hypothesized that this trend in the greater length of ICU and hospital stays for the NPH-8 group may be tangential to requiring twice as much insulin to achieve glycemic control despite lacking differences in Injury Severity Scores, inflammatory markers, presence of diabetes or obesity, carbohydrate intake, or pharmacotherapy known to worsen hyperglycemia (Table 3). This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.