PCOS patients with high DHEAS levels were younger and had higher 2 h insulin in the OGTT than those with low DHEAS levels [22.5 (20.25–26.75) vs. 24 (21.25–29.75) yrs, p < 0.05; 66.4 (38.97–114.9) vs. 45 (29.6–68.6) mU/L, p < 0.05, respectively], while BMI (p = 0.29), fasting insulin (p = 0.25) and HOMA-IR (p = 0.30) were not different between the three groups (Table 2). This evidence concerns the gene INS and polycystic ovary syndrome.