INS and type 1 diabetes mellitus: A recent report of an 11-center cross-sectional study in a large group of children with T1D using CGM with non-automated insulin delivery systems demonstrated that the median frequencies of TIR were 49%, 56%, 56%, and 61% in patients on isCGM with MDI, on rtCGM with MDI, on isCGM with an insulin pump, and on rtCGM with an insulin pump, respectively [18,22].