The results revealed that higher serum levels of IL-1 (OR = 2.35; 95% CI: 1.45–3.81; p < 0.001), IL-6 (OR = 1.87; 95% CI: 1.12–3.14; p < 0.001), and TNF-α (OR = 2.92; 95% CI: 1.76–4.89; p < 0.001) were all significantly associated with increased odds of HF. This evidence concerns the gene IL6 and hydrops fetalis.