LGALS3 and diabetes mellitus: In the German Diabetes Mellitus Dialysis (4D) study (1168 dialysis patients with type 2 diabetes mellitus; 4-year follow-up) and the Ludwigshafen Risk and Cardiovascular Health study (2579 patients with coronary angiograms; 10-year follow-up), the association between Gal-3, renal function, and adverse clinical outcomes was evaluated in two large patient cohorts.