Research conducted by Yu et al. in 2021 on cirrhotic rats, which focused on IL-6 levels, beta adrenergic receptors, and muscarinic receptors, concluded that in rats with cirrhosis, the levels of the pro-inflammatory cytokine IL-6 were elevated, whereas the expression of β1-AR protein and muscarinic M2 receptors was reduced. This evidence concerns the gene IL6 and Cirrhosis.