The concentrations of TRACP-5b with low handgrip strength (624.9 ± 250.9 vs. 449.8 ± 160.0 mU/dL, p < 0.001), low muscle mass (560.6 ± 223.2 vs. 440.0 ± 162.1 mU/dL, p < 0.001), and sarcopenia (643.8 ± 261.9 vs. 455.7 ± 165.6 mU/dL, p < 0.001) were significantly higher compared to those without and BMD of femoral neck with low handgrip strength (0.56 ± 0.12 vs. 0.67 ± 0.16 g/cm2, p = 0.002), low muscle mass (0.58 ± 0.14 vs. 0.68 ± 0.16 g/cm2, p = 0.001), and sarcopenia (0.54 ± 0.12 vs. 0.66 ± 0.16 g/cm2, p = 0.002) were significantly lower compared to those without (Figure 2). The gene discussed is ACP5; the disease is sarcopenia.