The PRRT2 gene, in our systematic review, appears to be the gene most involved in the development of paroxysmal dyskinesias that have an underlying genetic cause, contributing to the genesis especially of paroxysmal kinesigenic dyskinesias; we would like to specify that, as for example in the case of the Vaia et al. article from 2023 [26], it is pointed out that episodes of kinesigenic dyskinesia can originate as early as the age of 3 months of life. This evidence concerns the gene PRRT2 and episodic kinesigenic dyskinesia 1.