MUC1 and pulmonary fibrosis: The finding that TGF-ß1 can initiate a series of down-stream events forming a phospho-Smad3/MUC1-CT (MUC1-cytoplasmc tail) and MUC1-CT/β-catenin nuclear complex capable of enhancing conversion of alveolar epithelial type II cells and fibroblasts to myofibroblasts provides an explanation for its function in pulmonary fibrosis [130].