PRKN and malignant colon neoplasm: In glioma, melanoma, breast, lung, and colon cancers, the parkin/PARK2 gene has been identified as a mutation carrier (parkin, a gene implicated in autosomal recessive juvenile Parkinsonism, has also been proposed as a candidate tumor suppressor located on chromosome 6q25–q27) [137,138,139,140,141].