PTEN and cancer: In patients with Phosphatase and TENsin homolog deleted on chromosome 10 (PTEN) Hamartoma Tumor Syndrome (PHTS), an inherited cancer syndrome that predisposes patients to several other cancers, differences in gut microbiota were noted between individuals with and without cancer history, including increased Rikenellaceae and Eubacteriaceae, and decreased Bifidobacteriaceae and Clostridiaceae [20].