IRF3 and neoplasm: Through quantitative immunofluorescence analysis of tumor tissues, it was found that compared with the Model group and the cGAMP group, the liposome complex XA5508 significantly increased the expression levels of STING, p-STING, and IRF3 proteins (Figure 4D–F), demonstrating the activation of the cGAMP-STING-IRF3 signaling.