HDAC6 and non-Hodgkin lymphoma: In [74], hydroxamic acid (Figure 12) demonstrated potent inhibitory activity against HDAC6 and PI3K and antiproliferative activity against multiple non-Hodgkin’s lymphoma (NHL) cells, diffuse large B-cell lymphoma SU-DHL-6 cells, and mantle cell lymphoma JEKO-1 cells (IC50 value less than 0.1 μM).