Building upon this, Sun et al. suggested in 2025 that blocking CD93 could enhance intratumoral T cell infiltration by upregulating adhesion molecules (intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1) on tumor blood vessels, with T cells predominantly infiltrating tumors characterized by dysfunctional or immature vasculature [190]. The gene discussed is CD93; the disease is neoplasm.