The PLANET I study, conducted on 353 adults with T1D (47 patients) or T2D and proteinuria (UPCR 500–5000 mg/g), all on stable ACE-inhibitors or ARBs, followed the effect of atorvastatin 80 mg, rosuvastatin 10 mg, and rosuvastatin 40 mg on UPCR. This evidence concerns the gene ACE and type 2 diabetes mellitus.