In the 10 mg/kg groups compared to the control, the top ten affected pathways included histidine metabolism, biosynthesis of amino acids, cysteine and methionine metabolism; ABC transporters; thyroid hormone synthesis; aminoacyl-tRNA biosynthesis; alanine, aspartate, and glutamate metabolism; diabetic cardiomyopathy; ferroptosis; and glutathione metabolism. This evidence concerns the gene ABCG2 and diabetic cardiomyopathy.