In a distinct population, Sztolsztener et al. investigated apolipoprotein profiles in 58 childhood survivors of acute lymphoblastic leukemia (ALL), linking several apolipoproteins (APOA1, A2, C1, C3, H, J, and D) with obesity-related metabolic risk [105]. Here, APOA1 is linked to obesity due to melanocortin 4 receptor deficiency.