Evaluation of M344’s effects on the proliferation of NB cell lines by treatment with 4-(dimethylamino)-N-(1-(hydroxyamino)-7-oxoheptyl)benzamide (MTT) reagent in mouse and human MYCN-amplified (9464D and IMR-32) and non-amplified (Neuro-2a and SK-N-AS) cells lines revealed a stepwise decrease in NB cell proliferation in a time- and dose-dependent manner, affecting cell lines regardless of MYCN status (Figure 3A). Here, MYCN is linked to neuroblastoma.