SLC25A20 and atherosclerosis: It delineates how isoform-specific dysregulation of these transporters (e.g., VDAC1 downregulation impairing fatty acid oxidation in atherosclerosis, TRPC6-mediated Ca2+ influx driving cardiac fibrosis, and SLC25A20 deficiency promoting lipotoxicity) directly contributes to cardiovascular pathogenesis by disrupting mitochondrial calcium homeostasis, redox balance, metabolic flexibility, and organelle dynamics.