LC was characterized by an increase in IL-7, IL-8, IL-17F, IL-18, EGF, FGF-2, PDGF-AA, sCD40L, MCP-3 and a decrease in IL-4, IL-13, IL-22, IL-27, and FLT-3L. This evidence concerns the gene IL27 and laryngotracheoesophageal cleft.