AKT1 and cancer: This involves key proteins, such as Nrf2 and MAPK, in preventing cancer cell proliferation [22,23]; Src, NF-κB, and PI3K/Akt in promoting cancer cell apoptosis; and matrix metalloproteinases (MMP) secretion, Met overexpression, and Rho-Rac interaction in blocking cancer cell invasion and metastasis.