Moreover, combinatorial regimens incorporating lovastatin with the microtubule-stabilizing chemotherapeutic paclitaxel have demonstrated synergistic efficacy, characterized by enhanced intratumoural infiltration of cytotoxic CD8+ T lymphocytes, downmodulation of PD-L1 expression, and superior tumour growth control in both in vitro and in vivo experimental frameworks [269]. This evidence concerns the gene CD274 and neoplasm.