TP53 and neoplasm: Tumor-suppressive miRNAs (e.g., miR-26a, miR-125a-5p, miR-145-5p) restore or amplify p53 activity, whereas oncogenic miRNAs (e.g., miR-483-3p, miR-519d, miR-1228) suppress it, leading to unchecked growth and resistance.