ITGAM and neoplasm: Consistent with the results obtained from immunostaining of tumour tissues, from the analysis of the global protein profile, the expression of ICAM-1, VCAM-1, CD11b (a subset of dendritic cells), and MHC class I molecules (H2-D1 and H2-K1) were increased in PAK1KO tumour (Figure 6C) while CD31 and CD34, CD11c (a subset of dendritic cells), and MHC class II molecules (H2-Ab1, H2-Eb1, H2-DMa, and H2-DMb1) were significantly downregulated in PAK1KO tumours (Figure 6C).