Another paper, supporting the antiproliferative role of DUSP5, showed that DUSP5 KO mice show increased sensitivity to HRas (HRasQ61L)-driven papilloma formation in the 7,12-dimethylbenz[a]anthracene/12-O-tetradecanoylphorbol-13-acetate (DMBA/TPA) model of skin carcinogenesis. Here, DUSP5 is linked to papilloma.