According to the results of this study, the pro-BDNF/BDNF ratio was higher in children with ADHD, EEG anomalies, and significant cognitive and functional impairments, due to reduced BDNF levels, with no discernible variation in pro-BDNF levels, except in those with a history of febrile seizures [118]. This evidence concerns the gene BDNF and attention deficit-hyperactivity disorder.