Fu et al. (2025) reported that in a cohort of 2270 adult women from the NHANES database, AGP showed a strong positive association with NAFLD and liver fibrosis, with an inverted U-shaped relationship to CAP scores, suggesting that AGP levels may have a non-linear link with hepatic steatosis severity [4]. This evidence concerns the gene ATP5MK and metabolic dysfunction-associated steatotic liver disease.