Eb2Mab-12-mG2a and Eb2Mab-12-hG1 showed the antitumor effect against xenograft tumors of CHO/EphB2 (Figure 4), TNBC breast cancer MDA-MB-231 (Figure 6), and lung mesothelioma NCI-H226 (Figure 7). This evidence concerns the gene EPHB2 and breast cancer.