Meanwhile, IHC analysis, as shown in Figure 7B, demonstrated that the expressions of C-MYB protein in the tumor cells, as indicated with brown dots for both G51 treatment groups and the cisplatin group, were significantly decreased in comparison with the saline control group, confirming that G51 was also able to down-regulate c-myb in in vivo models, consistent with our in vitro Western blot experimental data. The gene discussed is MYB; the disease is neoplasm.