MAPT and early-onset autosomal dominant Alzheimer disease: With the present study, we also demonstrated the anti-amyloidogenic effect of the styrylquinolines toward amyloid β (Aβ1–42) and AcPHF6 (the hexapeptide 306VQIVYK311 segment from the microtubule binding region of Tau protein, which is known to promote nucleation dependent Tau-aggregation), both implicated in Alzheimer’s disease.