CDK6 and toxic multinodular goitre: The biological function and any known involvement in the pathophysiology of MNG, particularly recurrence, of the 11 candidate host genes are reported in Table S6: apart from CCND2 and CDK6, whose suppression within 34HR-MNG contrasts with their known oncogenic biological function, the altered expression of the remaining 9 host genes is in line with their documented oncogenic or tumor-suppressive functions.