ARHGAP32 and Alzheimer disease: Furthermore, reduced miR-132 expression in the hippocampus and medial frontal gyrus of AD patients (Braak scores 4 to 6) compared to non-demented controls (Braak scores 0 to 3) correlated with impairments in neuronal differentiation, mediated through the regulation of p250GAP, a Rho family GTPase enriched in the brain [164].