MAPT and Alzheimer disease: Validation analysis confirmed significant upregulation of miR-16-5p, miR-25-3p, miR-92a-3p, and miR-451a in prodromal AD patients, suggesting these dysregulated miRNAs are involved in the early progression of AD.Group of AD patients presented positive correlations between Aβ42 and miR-30b-5p (r = 0.67) and between h-tau and miR-223-3p (r = 0.62).