In addition, males showed positive correlations between IRF5, and the plasma insulin levels (r = 0.617, p = 0.014), homeostatic model assessment for insulin resistance (HOMA-IR) levels, r = 0.657, p = 0.008) and as well as a negative correlation with adiponectin (r = −0.543), although the latter showed only moderate statistical significance (p = 0.068, Table 2). This evidence concerns the gene INS and Insulin resistance.