IL1B and inflammatory bowel disease: In order to examine the effects of BSB on interleukin-1 (IL-1β), an indicator of inflammation in colon tissues, the rats were treated with BSB either 3 days before or 30 min after the induction of IBD and continued for 7 days, as shown in Figure 5A. In the control group (no IBD, no BSB), the 1L-1β level before IBD was 34.12 ± 5.45 pg/mg of protein.