RTCB and coinfection: Co-infection with T. bryosalmonae (Mc+) led to more pronounced suppression of muscle- and matrix-associated genes such as myosin light chain 3 (MYL3), troponin T2, cardiac type (TNNT2), natriuretic peptide receptor 2 (NPR2), matrix metallopeptidase 27 (MMP27), and RNA 2′,3′-cyclic phosphate, and 5′-OH ligase (RTCB).