EGFR and neoplasm: The epidermal growth factor receptor (EGFR), a transmembrane receptor tyrosine kinase that plays a central role in regulating various cellular processes, including survival, proliferation, and differentiation [22,23], has recently emerged as a promising target for tumor-specific delivery of photosensitizers, and several EGFR-targeting strategies, ranging from the use of monoclonal antibodies and EGF conjugates to small-molecule inhibitors and nanocarrier-based systems, have demonstrated encouraging results in enhancing cellular uptake, selectivity, and photodynamic efficacy [24,25,26].