In contrast, exosomal miR-196a remains elevated in cisplatin-resistant HNSCC through targeting cyclin-dependent kinase (CDK) N1B and inhibitor of growth family member 5 (ING5), indicating that this miRNA may serve as a promising predictor of cisplatin resistance and poor survival in HNSCC [62]. The gene discussed is ING5; the disease is head and neck squamous cell carcinoma.