No statistically significant associations were identified between any of the investigated IL-10 and NOS3 genotypes and BPD, or other neonatal complications analyzed, including RDS requiring mechanical ventilation, PDA, early-onset sepsis, intraventricular hemorrhage, pulmonary hemorrhage, ROP greater than stage 2, prolonged NICU stay, or death. This evidence concerns the gene NOS3 and Patent ductus arteriosus.