IL-17 may amplify the inflammatory cascade during AP, contributing to the severity of AP because it enhances neutrophil recruitment to the site of inflammation by increasing the transcription of proinflammatory cytokines (such as IL-1, IL-6, TNF-α) and neutrophil-attracting chemokine/cytokine [38,42,43]. The gene discussed is IL17A; the disease is alkaline phosphatase measurement.